A pioneering laboratory specializing in angiogenesis, genome editing, metabolism and drug discovery.

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Our Topics

Gene Editing

– Transgenic mice (inducible Cre)

– BAC modification

– Gene trapping (Cre/Loxp; Dre/Roxp)

– ES cell targeting

– Lineage tracing

– Recombinase mice (Cre/Dre/Flp)


Angiogenesis

– Venous endothelium

– Endothelail cell (EC) migration

– Oxygen induced retinopathy (OIR)

– Arteriovenous malformation (AVM)

– Tumor endothelium

– EC-Macrophage interaction

– CNS vasculature

Metabolism

– Carbon tracing (C13)

– Glucose metabolism

– Fatty acid metabolism 

– Lactate metabolism

– Endothelial metabolism

– Brain metabolism

 

 

Bioinformatics

– scRNAseq

– Seurat analysis

– Monocle analysis

– R studio

– Endothelial scRNAseq

 

Gallery